当前,很少有DNA测试公司,例如23andMe,AncestryDNA等。这些公司可用于根据DNA预测您或您的孩子患湿疹的风险。请记住,这些只是预测而已,并不是确切的结论,环境中的条件仍然起着至关重要的作用。
与湿疹相关的其他基因在《自然通讯》杂志上发表的另一项由玛丽安娜·史蒂文斯(Mariana L Stevens)领导的新研究中,研究人员发现并划定了基因KIF3A的两个变异,据说这两个变异导致调节水分流失的皮肤屏障受损。导致湿疹发作。
由玛丽安娜·史蒂文斯(Mariana L Stevens)领导的小组进行的研究得出的结论可能会促使研究人员提出基因测试,以用于诊断婴儿患特应性湿疹的风险。这可能有助于及早发现病情,并可能导致提出针对皮肤水分流失的疗法。因此,如美国国立卫生研究院。
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L. Paternoster, M. Standl, J. Waage et al., “Multi-ancestry genome-wide association study of 21, 000 cases and 95, 000 controls identifies new risk loci for atopic dermatitis,” Nature Genetics, vol. 47, no. 12, pp. 1449–1456, 2015.
M. Pigors, J. E. A. Common, X. F. C. C. Wong et al., “Exome sequencing and rare variant analysis reveals multiple filaggrin mutations in bangladeshi families with atopic eczema and additional risk genes,” Journal of Investigative Dermatology, vol. 138, no. 12, pp. 2674–2677, 2018.
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